When will I start seeing results?

Most patients notice improvements in skin clarity and texture within 2–4 weeks of twice-daily use. The clinical trial results — including measurable improvements in fine lines, firmness, and radiance — were recorded at 12 weeks. For best results, use consistently every morning and evening, and always follow with sunscreen in the morning.

Can I use this with retinol, acids, or other actives?

Yes. The recommended approach is to use the Vitamin C Pro-Collagen Serum in the morning and retinol in the evening to avoid unnecessary overlap. It pairs well with hyaluronic acid, peptide serums, and ceramide moisturizers. If you use AHAs or BHAs, reserve those for every other evening to minimize cumulative irritation. Always introduce new products one at a time and conduct a patch test first.

How does the elife Shop subscription work?

Select the subscription option at checkout to receive your serum at a reduced monthly price, delivered automatically. You can skip a shipment or cancel anytime after your second order is complete — no long-term commitment required. Subscriptions can be managed directly from your elife Shop account.

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Vitamin C Pro-Collagen Serum - Clinical Skin

Name: Vitamin C Pro-Collagen Serum - Clinical Skin
Brand: elife公式ショップ
SKU: SKIN-Cli-Vit-15ml-bottle-000000
Price: 9980.0 JPY
Availability: InStock

Vitamin C Pro-Collagen Serum - Clinical Skin

¥9,980

Sale Sold out

You've tried Vitamin C serums before. You've dealt with the sting, the oxidation, the serum that turned orange in three weeks. You kept going because the idea was right — but the formula wasn't.

This is the one that gets the formula right.

The Clinical+ Skin Vitamin C Pro-Collagen Serum was developed at the intersection of pharmaceutical science and skincare. Every ingredient serves a function. Every concentration was chosen for a reason. And the result — clinically measured over 12 weeks on a panel of real patients — speaks for itself.

+23% improvement in skin radiance. +21.2% reduction in fine lines and wrinkles. +18.6% improvement in skin lift and firmness.

No redness. No peeling. Zero irritation — confirmed at every evaluation point throughout the study.

Why This Serum Is Different

Most Vitamin C serums rely on a single form of ascorbic acid — effective in theory, unstable in practice. It oxidizes, loses potency, and for many patients, causes irritation before it delivers results.

Clinical+ Skin takes a different approach. The Pro-Collagen Serum combines 20% L-Ascorbic Acid — the most bioavailable form of Vitamin C — with Tetrahexyldecyl Ascorbate, a stable, oil-soluble derivative that penetrates deeper layers of the skin. Together, they deliver immediate brightening and sustained collagen stimulation, without the instability or irritation risk of a single-form formula.

This dual approach is made possible by Clinical+'s patented A.C.E. Technology — a delivery system designed to protect active ingredients, enhance penetration, and work in harmony with the skin's own defense mechanisms.

The A.C.E. Technology Difference

ACE stands for the three pillars of the formula:

Antioxidant Enzyme Defense — Superoxide Dismutase (SOD), a high-speed antioxidant enzyme, neutralizes the free radicals that trigger inflammation at the cellular level. This addresses inflammaging — the chronic, low-grade inflammation behind wrinkles, loss of firmness, and uneven tone.

C & E Antioxidant Complex — Vitamins C and E work together, with Vitamin E stabilizing Ascorbic Acid and amplifying its efficacy. Glutathione — the master antioxidant — and rare Ergothioneine extend this protection across every layer of the skin.

Essential Ceramide Barrier — Ceramides AP, EOP, NG, and NP rebuild the skin's lipid barrier, locking in moisture and shielding the deeper work from external stressors.

The amber color of this serum is not a flaw. It is evidence — the visible signature of high-concentration Glutathione and CoQ10.

Clinically Tested. Dermatologist-Validated. Safe for Sensitive Skin.

Clinical+ Skin was founded on a single commitment: results that are measurable, not just marketable. The Pro-Collagen Serum was evaluated in an independent 12-week clinical efficacy study conducted by Essex Testing Clinic, Inc. (Verona, NJ), under the supervision of a board-certified dermatologist and toxicologist.

27 female subjects, ages 46–63, used the serum twice daily. Skin radiance, fine lines and wrinkles, firmness, elasticity, and sagging were measured at baseline, 6 weeks, and 12 weeks — through trained technician evaluation, Cutometer® biometric measurements, digital image analysis, and high-density ultrasound imaging.

At 12 weeks: 100% of subjects showed improvement in both skin radiance and fine lines.

No irritation was observed on any subject at any evaluation point throughout the study.

About Clinical+ Skin

Clinical+ Skin is a New York-based cosmeceutical brand founded in 2022 by Israel Zahler (CEO, 20+ years in health and wellness) and Ewelina Aiossa (CMO, former L'Oréal formulation expert). Their mission: treat skincare like medicine.

Every product is clinically tested, dermatologist-validated, and formulated with peer-reviewed science — occupying the space between a luxury brand and a prescription clinic. Featured in Marie Claire, InStyle, US Magazine, and MedEsthetics. Winner of a 2022 NewBeauty Award.

elife Shop is the exclusive authorized retailer of Clinical+ Skin in Japan.